abstract：OBJECTIVE:Contemporary deep brain stimulation (DBS) for Parkinson's disease is delivered continuously, and adjustments based on patient's changing symptoms must be made manually by a trained clinician. Patients may be subjected to energy intensive settings at times when they are not needed, possibly resulting in stimul...

journal_title：Journal of neural engineering

authors： Swann NC,de Hemptinne C,Thompson MC,Miocinovic S,Miller AM,Gilron R,Ostrem JL,Chizeck HJ,Starr PA

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:When designing multiclass motor imagery-based brain-computer interface (MI-BCI), a so-called tangent space mapping (TSM) method utilizing the geometric structure of covariance matrices is an effective technique. This paper aims to introduce a method using TSM for finding accurate operational frequency bands r...

journal_title：Journal of neural engineering

authors： Islam MR,Tanaka T,Molla MKI

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:Recording of neural signals from intact peripheral nerves in patients with spinal cord injury or stroke survivors offers the possibility for the development of closed-loop sensorimotor prostheses. Nerve cuffs have been found to provide stable recordings from peripheral nerves for prolonged periods of time. Ho...

journal_title：Journal of neural engineering

authors： Silveira C,Brunton E,Spendiff S,Nazarpour K

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:Resting state functional connectivity (RSFC) allows the study of functional organization in normal and diseased brain by measuring the spontaneous brain activity generated under resting conditions. Intrinsic optical signal imaging (IOSI) based on multiple illumination wavelengths has been used successfully to...

journal_title：Journal of neural engineering

authors： Kura S,Xie H,Fu B,Ayata C,Boas DA,Sakadžić S

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:Intracortical brain-machine interfaces (iBMIs) aim to restore efficient communication and movement ability for paralyzed patients. However, frequent recalibration is required for consistency and reliability, and every recalibration will require relatively large most current sample set. The aim in this study i...

journal_title：Journal of neural engineering

authors： Zhang P,Ma X,Chen L,Zhou J,Wang C,Li W,He J

更新日期：2018-04-01 00:00:00

abstract：:This review paper shows that tungsten should not generally be used as a chronically implanted material. The metal has a long implant history, from neuroscience, vascular medicine, radiography, orthopaedics, prosthodontics, and various other fields, primarily as a result of its high density, radiopacity, tensile streng...

journal_title：Journal of neural engineering

authors： Shah Idil A,Donaldson N

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:We recently developed soft neural interfaces enabling the delivery of electrical and chemical stimulation to the spinal cord. These stimulations restored locomotion in animal models of paralysis. Soft interfaces can be placed either below or above the dura mater. Theoretically, the subdural location combines ...

journal_title：Journal of neural engineering

authors： Capogrosso M,Gandar J,Greiner N,Moraud EM,Wenger N,Shkorbatova P,Musienko P,Minev I,Lacour S,Courtine G

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Brain-computer interface (BCI) technology aims to provide individuals with paralysis a means to restore function. Electrocorticography (ECoG) uses disc electrodes placed on either the surface of the dura or the cortex to record field potential activity. ECoG has been proposed as a viable neural recording moda...

journal_title：Journal of neural engineering

authors： Degenhart AD,Hiremath SV,Yang Y,Foldes S,Collinger JL,Boninger M,Tyler-Kabara EC,Wang W

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Damage to the brain, as a result of various medical conditions, impacts the everyday life of patients and there is still no complete cure to neurological disorders. Neuroprostheses that can functionally replace the damaged neural circuit have recently emerged as a possible solution to these problems. Here we ...

journal_title：Journal of neural engineering

authors： Xu T,Xiao N,Zhai X,Kwan Chan P,Tin C

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:Despite the high number of degrees of freedom of the human hand, most actions of daily life can be executed incorporating only palmar, pincer and lateral grasp. In this study we attempt to discriminate these three different executed reach-and-grasp actions utilizing their EEG neural correlates. APPROACH:In a...

journal_title：Journal of neural engineering

authors： Schwarz A,Ofner P,Pereira J,Sburlea AI,Müller-Putz GR

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:This paper discusses the invariance and variability in interaction error-related potentials (ErrPs), where a special focus is laid upon the factors of (1) the human mental processing required to assess interface actions (2) time (3) subjects. APPROACH:Three different experiments were designed as to vary prim...

journal_title：Journal of neural engineering

authors： Abu-Alqumsan M,Kapeller C,Hintermüller C,Guger C,Peer A

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:Neural reflexes regulate immune responses and homeostasis. Advances in bioelectronic medicine indicate that electrical stimulation of the vagus nerve can be used to treat inflammatory disease, yet the understanding of neural signals that regulate inflammation is incomplete. Current interfaces with the vagus n...

journal_title：Journal of neural engineering

authors： Caravaca AS,Tsaava T,Goldman L,Silverman H,Riggott G,Chavan SS,Bouton C,Tracey KJ,Desimone R,Boyden ES,Sohal HS,Olofsson PS

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:The reliable estimation of parameters such as mean or covariance matrix from noisy and high-dimensional observations is a prerequisite for successful application of signal processing and machine learning algorithms in brain-computer interfacing (BCI). This challenging task becomes significantly more difficult...

journal_title：Journal of neural engineering

authors： Samek W,Nakajima S,Kawanabe M,Müller KR

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:In biomagnetic signal processing, the theory of the signal subspace has been applied to removing interfering magnetic fields, and a representative algorithm is the signal space projection algorithm, in which the signal/interference subspace is defined in the spatial domain as the span of signal/interference-s...

journal_title：Journal of neural engineering

authors： Sekihara K,Nagarajan SS

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:Brain-machine interfaces (BMIs) have been proposed in closed-loop applications for neuromodulation and neurorehabilitation. This study describes the impact of different feedback modalities on the performance of an EEG-based BMI that decodes motor imagery (MI) of leg flexion and extension. APPROACH:We execute...

journal_title：Journal of neural engineering

authors： Liu D,Chen W,Lee K,Chavarriaga R,Bouri M,Pei Z,Del R Millán J

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:Over the past two decades retinal prostheses have made major strides in restoring functional vision to patients blinded by diseases such as retinitis pigmentosa. Presently, implants use single pulses to activate the retina. Though this stimulation paradigm has proved beneficial to patients, an unresolved prob...

journal_title：Journal of neural engineering

authors： Sekhar S,Jalligampala A,Zrenner E,Rathbun DL

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:The aim of this paper was to characterize brain non-stationarity during an auditory oddball task in schizophrenia (SCH). The level of non-stationarity was measured in the baseline and response windows of relevant tones in SCH patients and healthy controls. APPROACH:Event-related potentials were recorded from...

journal_title：Journal of neural engineering

authors： Núñez P,Poza J,Bachiller A,Gomez-Pilar J,Lubeiro A,Molina V,Hornero R

更新日期：2017-08-01 00:00:00

abstract：:Retinal implants have proven their ability to restore visual sensation to people with degenerative retinopathy, characterized by photoreceptor cell death and the retina's inability to sense light. Retinal bionics operate by electrically stimulating the surviving neurons in the retina, thus triggering the transfer of v...

journal_title：Journal of neural engineering

authors： Bareket L,Barriga-Rivera A,Zapf MP,Lovell NH,Suaning GJ

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:The vision of bioelectronic medicine is to treat disease by modulating the signaling of visceral nerves near various end organs. In small animal models, the nerves of interest can have small diameters and limited surgical access. New high-resolution methods for building nerve interfaces are desirable. In this...

journal_title：Journal of neural engineering

authors： Lissandrello CA,Gillis WF,Shen J,Pearre BW,Vitale F,Pasquali M,Holinski BJ,Chew DJ,White AE,Gardner TJ

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:Spike detection from extracellular recordings is a crucial preprocessing step when analyzing neuronal activity. The decision whether a specific part of the signal is a spike or not is important for any kind of other subsequent preprocessing steps, like spike sorting or burst detection in order to reduce the c...

journal_title：Journal of neural engineering

authors： Lieb F,Stark HG,Thielemann C

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:Differential measurement of efferent and afferent peripheral nerve activity offers a promising means of improving the clinical utility of implantable neuroprostheses. The tripolar nerve cuff electrode has historically served as the gold standard for achieving high signal-to-noise ratios (SNRs) of the recordin...

journal_title：Journal of neural engineering

authors： Sabetian P,Popovic MR,Yoo PB

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:Electroencephalography (EEG) offers a unique opportunity to study human neural activity non-invasively with millisecond resolution using minimal equipment in or outside of a lab setting. EEG can be combined with a number of techniques for closed-loop experiments, where external devices are driven by specific ...

journal_title：Journal of neural engineering

authors： Black C,Voigts J,Agrawal U,Ladow M,Santoyo J,Moore C,Jones S

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:Brain-computer interfaces (BCIs) can help patients who have lost control over most muscles but are still conscious and able to communicate or interact with the environment. One of the most popular types of BCI is the P300-based BCI. With this BCI, users are asked to count the number of appearances of target s...

journal_title：Journal of neural engineering

authors： Jin J,Zhang H,Daly I,Wang X,Cichocki A

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:Neuromusculoskeletal models involve many subject-specific physiological parameters that need to be adjusted to adequately represent muscle properties. Traditionally, neuromusculoskeletal models have been calibrated with a forward-inverse dynamic optimization which is time-consuming and unfeasible for rehabili...

journal_title：Journal of neural engineering

authors： Bueno DR,Montano L

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:Brain-computer interfaces (BCIs) implemented with real-time functional magnetic resonance imaging (rt-fMRI) use fMRI time-courses from predefined regions of interest (ROIs). To reach best performances, localizer experiments and on-site expert supervision are required for ROI definition. To automate this step,...

journal_title：Journal of neural engineering

authors： Lührs M,Sorger B,Goebel R,Esposito F

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:Dry electrodes have an advantage over gel-based 'wet' electrodes by providing quicker set-up time for electroencephalography recording; however, the potentially poorer contact can result in noisier recordings. We examine the impact that this may have on brain-computer interface communication and potential app...

journal_title：Journal of neural engineering

authors： Clements JM,Sellers EW,Ryan DB,Caves K,Collins LM,Throckmorton CS

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:While motor-imagery based brain-computer interfaces (BCIs) have been studied over many years by now, most of these studies have taken place in controlled lab settings. Bringing BCI technology into everyday life is still one of the main challenges in this field of research. APPROACH:This paper systematically ...

journal_title：Journal of neural engineering

authors： Brandl S,Frølich L,Höhne J,Müller KR,Samek W

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:Schwann cells (SCs) are primary structural and functional cells in the peripheral nervous system. These cells play a crucial role in peripheral nerve regeneration by releasing neurotrophic factors. This study evaluated the neural differentiation potential effects of stem cells from human exfoliated deciduous ...

journal_title：Journal of neural engineering

authors： Su WT,Pan YJ

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:In spite of intense theoretical and experimental investigations on electrical nerve stimulation, the influence of reversed ion currents on network activity during extracellular stimulation has not been investigated so far. APPROACH:Here, the impact of calcium current reversal on neurotransmitter release duri...

journal_title：Journal of neural engineering

authors： Werginz P,Rattay F

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:We have previously demonstrated a brain-machine interface neuroprosthetic system that provided continuous control of functional electrical stimulation (FES) and restoration of grasp in a primate model of spinal cord injury (SCI). Predicting intended EMG directly from cortical recordings provides a flexible hi...

journal_title：Journal of neural engineering

authors： Ethier C,Acuna D,Solla SA,Miller LE

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:Loss of even part of the upper limb is a devastating injury. In order to fully restore natural function when lacking sufficient residual musculature, it is necessary to record directly from peripheral nerves. However, current approaches must make trade-offs between signal quality and longevity which limit the...

journal_title：Journal of neural engineering

authors： Irwin ZT,Schroeder KE,Vu PP,Tat DM,Bullard AJ,Woo SL,Sando IC,Urbanchek MG,Cederna PS,Chestek CA

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:Implantable brain-computer interface (BCI) research promises improvements in human health and enhancements in quality of life. Informed consent of subjects is a central tenet of this research. Rapid advances in neuroscience, and the intimate connection between functioning of the brain and conceptions of the s...

journal_title：Journal of neural engineering

authors： Klein E,Ojemann J

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:In electroencephalographic (EEG) data, signals from distinct sources within the brain are widely spread by volume conduction and superimposed such that sensors receive mixtures of a multitude of signals. This reduction of spatial information strongly hampers single-trial analysis of EEG data as, for example, ...

journal_title：Journal of neural engineering

authors： Sannelli C,Vidaurre C,Müller KR,Blankertz B

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:Signal attenuation is a major problem facing intracortical sensors for chronic neuroprosthetic applications. Many studies suggest that failure is due to gliosis around the electrode tips, however, mechanical and material causes of failure are often overlooked. The purpose of this study was to investigate the ...

journal_title：Journal of neural engineering

authors： Barrese JC,Aceros J,Donoghue JP

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Patients with amyotrophic lateral sclerosis (ALS) may benefit from brain-computer interfaces (BCI), but the utility of such devices likely will have to account for the functional, cognitive, and behavioral heterogeneity of this neurodegenerative disorder. APPROACH:In this study, a heterogeneous group of pati...

journal_title：Journal of neural engineering

authors： Geronimo A,Simmons Z,Schiff SJ

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Medical implants made of non-biological materials provoke a chronic inflammatory response, resulting in the deposition of a collagenous scar tissue (ST) layer on their surface, that gradually thickens over time. This is a critical problem for neural interfaces. Scar build-up on electrodes results in a progres...

journal_title：Journal of neural engineering

authors： FitzGerald JJ

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVES:We aimed to develop a robotic interface capable of providing finely-tuned, multidirectional trunk assistance adjusted in real-time during unconstrained locomotion in rats and mice. APPROACH:We interfaced a large-scale robotic structure actuated in four degrees of freedom to exchangeable attachment modules e...

journal_title：Journal of neural engineering

authors： von Zitzewitz J,Asboth L,Fumeaux N,Hasse A,Baud L,Vallery H,Courtine G

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Current mapping of epileptic networks in patients prior to epilepsy surgery utilizes electrode arrays with sparse spatial sampling (∼1.0 cm inter-electrode spacing). Recent research demonstrates that sub-millimeter, cortical-column-scale domains have a role in seizure generation that may be clinically signifi...

journal_title：Journal of neural engineering

authors： Vanleer AC,Blanco JA,Wagenaar JB,Viventi J,Contreras D,Litt B

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:State of the art brain-computer interface (BCI) research focuses on improving individual components such as the application or the decoder that converts the user's brain activity to control signals. In this study, we investigate the interaction between these components in the P300 speller, a BCI for communica...

journal_title：Journal of neural engineering

authors： Verhoeven T,Buteneers P,Wiersema JR,Dambre J,Kindermans PJ

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:The advancement of surface electromyogram (sEMG) recording and signal processing techniques has allowed us to characterize the recruitment properties of a substantial population of motor units (MUs) non-invasively. Here we seek to determine whether MU recruitment properties are modified in paretic muscles of ...

journal_title：Journal of neural engineering

authors： Hu X,Suresh AK,Rymer WZ,Suresh NL

更新日期：2015-12-01 00:00:00